Depression is a mix of biological, genetic & psychological factors. At the biological level, depression results from abnormal levels of sure neurotransmitters in the brain. This can be caused by changing levels of hormones, explaining why lots of people first experience depression in the coursework of puberty. a few the more common factors involved in depression are:
Relatives history. Genetics play an important part in depression. It can run in families for generations.
Trauma & stress. Things like financial issues, the breakup of a relationship, or the death of a loved can bring on depression. You can become depressed after changes in your life, like beginning a brand spanking new job, Pessimistic character. Individuals who have low self-esteem as well as a negative outlook are at higher risk of becoming depressed. These traits may well be caused by low-level depression (called dysthymia).
Physical conditions. Serious medical conditions like heart disease, cancer, & HIV can contribute to depression, partly because of the physical weakness & stress they bring on. Depression can make medical conditions worse, since it weakens the immune process & can make pain harder to bear. In some cases, depression can be caused by medications used to treat medical conditions.
Other psychological disorders. Anxiety disorders, eating disorders, schizophrenia, & () substance abuse often appear along with depression.
What Causes depression? The multiple causes of depression are not understood. Current research suggests feasible genetic, familial, biochemical, physical, psychological, & social causes. Psychological causes (the focus of lots of nursing interventions) may include feelings of helplessness & vulnerability, anger, hopelessness & pessimism, & low self-esteem. They may be related to abnormal character & behavior patterns & troubled personal relationships. In lots of patients, the history identifies a specific personal loss or extreme stressor that probably interacts with the person's predisposition to provoke major depression. Depression may be secondary to a specific medical condition, for example:
Drugs prescribed for medical & psychiatric conditions as well as lots of often abused substances can also cause depression. Examples include antihypertensives, psychotropics, narcotic & nonnarcotic analgesics, antiparkinsonian drugs, numerous cardiovascular medications, oral anti diabetics, antimicrobials, steroids, chemotherapeutic agents, cimetidine, & alcohol. Individuals who have low self-esteem, who consistently view themselves & the world with pessimism or who are readily overwhelmed by stress, are liable to depression. Whether this represents a psychological predisposition or an early type of the disease is not clear. It is important to keep in mind that all of the depressive disorders are treatable conditions.
metabolic disturbances, such as hypoxia & hypercalcemia
endocrine disorders, such as diabetes & Cushing's syndrome
neurologic diseases, such as Parkinson's disease & Alzheimer's disease
cancer ( of the pancreas)
viral & bacterial infections, such as influenza & pneumonia
cardiovascular disorders such as heart failure
pulmonary disorders such as chronic obstructive pulmonary disease
musculoskeletal disorders such as degenerative arthritis
GI disorders such as irritable bowel syndrome
genitourinary issues such as incontinence
collagen vascular diseases such as lupus
anemia
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